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La biota intestinal, el metabolismo energético, y la Diabetes mellitus
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oxÃgeno, la distribución topográfica en el tubo digestivo, y la familia de pertenencia (establecida ésta de la composición nucleotÃdica del genoma bacteriano). Los Firmicutes y los Bacteroidetes son las familias bacterianas predominantes en el intestino. Los
cambios en los estilos dietéticos y alimentarios del sujeto, con una reducción del consumo de fibra dietética, y un aumento de la presencia de azúcares y cereales refinadas, y grasas saturadas, provocan cambios profundos en la composición bacteriana de la biota intestinal que pueden desembocar en inflamación, resistencia periférica a la acción de la insulina, deposición incrementada de grasa corporal y visceral, y exceso de peso. La comprensión de los mecanismos etio- y fisiopatopgénicos mediante los cuales la biota
intestinal influye en el metabolismo energético puede aportar nuevas estrategias para la prevención y el tratamiento de la obesidad y las comorbilidades acompañantes incluidas en el SÃndrome metabólico.
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